Factor V Leiden and Prothrombin 20210A Mutations among Turkish Pediatric Leukemia Patients.
Leuk Res Treatment
; 2012: 250432, 2012.
Article
em En
| MEDLINE
| ID: mdl-23198154
ABSTRACT
This study was undertaken to determine the prevalence of the Factor V 1691 G-A and PT 20210 G-A mutations in Turkish children with leukemia. We genotyped 135 pediatric leukemia patients with for these mutations. Eleven (8%) of the 135 patients were heterozygous for the FV 1691 G-A mutation. Seven (5,1%) of the patients carried the PT 20210 G-A heterozygous mutation. Of the 135 patients, only three had thrombotic event, none of which had these two mutations, which is common in Turkish population. Our findings revealed a controversial compared to the previous reports, which needs further investigation.
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Bases de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
Leuk Res Treatment
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Turquia