Synthesis of antioxidants for prevention of age-related macular degeneration.
J Nat Prod
; 76(3): 450-4, 2013 Mar 22.
Article
em En
| MEDLINE
| ID: mdl-23346866
ABSTRACT
Photooxidation of A2E may be involved in diseases of the macula, and antioxidants could serve as therapeutic agents for these diseases. Inhibitors of A2E photooxidation were prepared by Mannich reaction of the antioxidant quercetin. These compounds contain water-solubilizing amine groups, and several were more potent inhibitors of A2E photooxidation than quercetin.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Compostos de Piridínio
/
Retinoides
/
Degeneração Macular
/
Antioxidantes
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos