Update on clinical trials for the prevention of acute kidney injury in patients undergoing cardiac surgery.
Am J Surg
; 206(1): 86-95, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23411349
ABSTRACT
BACKGROUND:
Effective therapeutic agents for the prevention and treatment of acute kidney injury (AKI) after cardiac surgery remain elusive despite the tremendous advances in surgical techniques, technology, and understanding of disease processes. Recent developments and their effect on the incidence of AKI after cardiac surgery are discussed. DATA SOURCES Published clinical trials in PubMed, strength of evidence assessed by the guidelines of the American Family Physicians.CONCLUSIONS:
The definition of AKI has changed, and the focus of interventions has shifted from treatment to prevention to recovery from AKI. Antioxidants and biological agents have been added to classic armaments of hydration and diuretics in addition to tighter metabolic control to prevent AKI. Although the treatment options remain unsatisfactory, a lot of progress nevertheless continues to be made in the prevention and treatment of AKI.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Fármacos Cardiovasculares
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Ponte de Artéria Coronária sem Circulação Extracorpórea
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Injúria Renal Aguda
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Hidratação
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Procedimentos Cirúrgicos Cardíacos
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Hipotermia Induzida
Tipo de estudo:
Etiology_studies
/
Guideline
Limite:
Humans
Idioma:
En
Revista:
Am J Surg
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos