Does exposure to stressors predict changes in physiological dysregulation?
Ann Behav Med
; 46(1): 121-6, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-23526059
ABSTRACT
BACKGROUND:
The allostatic load framework implies that cumulative exposure to stressors results in multi-system physiological dysregulation.PURPOSE:
The purpose of this study was to investigate the effect of stress burden on subsequent changes (2000-2006) in physiological dysregulation.METHODS:
Data came from a population-based cohort study in Taiwan (n = 521, aged 54+ in 2000, re-examined in 2006). Measures of stressful events and chronic strain were based on questions asked in 1996, 1999, and 2000. A measure of trauma was based on exposure to the 1999 earthquake. Dysregulation was based on 17 biomarkers (e.g., metabolic, inflammatory, neuroendocrine).RESULTS:
There were some small effects among men chronic strain was associated with subsequent increases in dysregulation (standardized ß = 0.08, 95 % CI = 0.01 to 0.20), particularly inflammation; life events were also associated with increased inflammation (ß = 0.10, CI = 0.01 to 0.26). There were no significant effects in women.CONCLUSIONS:
We found weak evidence that stress burden is associated with changes in dysregulation.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Estresse Psicológico
/
Alostase
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Ann Behav Med
Assunto da revista:
CIENCIAS DO COMPORTAMENTO
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos