MEME-LaB: motif analysis in clusters.
Bioinformatics
; 29(13): 1696-7, 2013 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-23681125
ABSTRACT
SUMMARY:
Genome-wide expression analysis can result in large numbers of clusters of co-expressed genes. Although there are tools for ab initio discovery of transcription factor-binding sites, most do not provide a quick and easy way to study large numbers of clusters. To address this, we introduce a web tool called MEME-LaB. The tool wraps MEME (an ab initio motif finder), providing an interface for users to input multiple gene clusters, retrieve promoter sequences, run motif finding and then easily browse and condense the results, facilitating better interpretation of the results from large-scale datasets.AVAILABILITY:
MEME-LaB is freely accessible at http//wsbc.warwick.ac.uk/wsbcToolsWebpage/. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Fatores de Transcrição
/
Software
/
Regiões Promotoras Genéticas
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Reino Unido