Molecular epidemiology of influenza A (H5N1) viruses, Bangladesh, 2007-2011.
Prev Vet Med
; 111(3-4): 314-8, 2013 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-23820377
ABSTRACT
To investigate the origins, evolution and patterns of spread of HPAI H5N1 outbreaks in Bangladesh, we performed a phylogenetic reconstruction analysis using Bayesian methods. The analysis was conducted using 81 hemagglutinin (HA) gene sequences from the H5N1 viruses isolated in Bangladesh from 2007 to 2011, together with 264 publicly available HA sequences of clade 2.2, 2.3.2 and 2.3.4 retrieved from GenBank. Our study provides evidence that clade 2.2.2 viruses that caused outbreaks in Bangladesh were lineages independent from the viruses introduced earlier into India. Furthermore, the Bangladesh clade 2.2.2 descendents subsequently spread to India and Bhutan. This has implications for avian influenza control in southern Asia suggesting multiple routes of entry of the virus including one pathway that spread to neighboring countries via Bangladesh.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Doenças das Aves Domésticas
/
Galinhas
/
Surtos de Doenças
/
Influenza Humana
/
Influenza Aviária
Tipo de estudo:
Screening_studies
Limite:
Animals
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Prev Vet Med
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Bangladesh