Hippocampal neurogenesis in Alzheimer's disease: is there a role for dietary modulation?
J Alzheimers Dis
; 38(1): 11-38, 2014.
Article
em En
| MEDLINE
| ID: mdl-23948932
ABSTRACT
Alterations in hippocampal neurogenesis have been recognized as an integral part of Alzheimer's disease. Adult hippocampal neurogenesis is regulated by intrinsic and extrinsic factors; one of them is diet. This review provides an assessment of the current state of the field in hippocampal neurogenesis studies in Alzheimer's disease and focuses on the role of diet. The review highlights some of the key dietary compounds and interventions such as calorie restriction, fat, polyphenols, zinc, folate, alcohol and thiamine, and emphasizes the pathways that they modify.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Dieta
/
Neurogênese
/
Doença de Alzheimer
/
Hipocampo
Limite:
Humans
Idioma:
En
Revista:
J Alzheimers Dis
Assunto da revista:
GERIATRIA
/
NEUROLOGIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Reino Unido