Recurrent H3.3 alterations in childhood tumors.
Nat Genet
; 45(12): 1413-4, 2013 Dec.
Article
em En
| MEDLINE
| ID: mdl-24270444
ABSTRACT
Comprehensive sequencing of benign and malignant tumors has recently uncovered new driver mutations in childhood tumors. A new report now describes frequent histone H3.3 alterations in chondroblastoma and giant cell tumor of bone, emphasizing the importance of this histone variant in pediatric cancers.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Ósseas
/
Histonas
/
Condroblastoma
/
Tumor de Células Gigantes do Osso
Limite:
Humans
Idioma:
En
Revista:
Nat Genet
Assunto da revista:
GENETICA MEDICA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Alemanha