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The orally available Btk inhibitor ibrutinib (PCI-32765) protects against osteoclast-mediated bone loss.
Shinohara, Masahiro; Chang, Betty Y; Buggy, Joseph J; Nagai, Yusuke; Kodama, Tatsuhiko; Asahara, Hiroshi; Takayanagi, Hiroshi.
Afiliação
  • Shinohara M; Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549, Japan; Department of Systems BioMedicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45,
  • Chang BY; Pharmacyclics, Inc., Research Department, Sunnyvale, CA 94085-4521, USA.
  • Buggy JJ; Pharmacyclics, Inc., Research Department, Sunnyvale, CA 94085-4521, USA.
  • Nagai Y; Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549, Japan; Department of Immunology, Graduate School of Medicine, The University of Tokyo, Japan; Japan Science and Technology Agency (JST), Explo
  • Kodama T; Department of Molecular Biology and Medicine, Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo 153-8904, Japan.
  • Asahara H; Department of Systems BioMedicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8510, Japan.
  • Takayanagi H; Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549, Japan; Department of Immunology, Graduate School of Medicine, The University of Tokyo, Japan; Japan Science and Technology Agency (JST), Explo
Bone ; 60: 8-15, 2014 Mar.
Article em En | MEDLINE | ID: mdl-24316417
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Reabsorção Óssea / Proteínas Tirosina Quinases / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bone Assunto da revista: METABOLISMO / ORTOPEDIA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Reabsorção Óssea / Proteínas Tirosina Quinases / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bone Assunto da revista: METABOLISMO / ORTOPEDIA Ano de publicação: 2014 Tipo de documento: Article