Very strong organosuperbases formed by combining imidazole and guanidine bases: synthesis, structure, and basicity.
Angew Chem Int Ed Engl
; 53(5): 1435-8, 2014 Jan 27.
Article
em En
| MEDLINE
| ID: mdl-24339377
ABSTRACT
New structural motives for organosuperbases, that are easy to prepare and highly basic are urgently required in many areas of chemistry. The synthesis of N,N'-bis(imidazolyl)guanidine bases (BIG bases) is reported. Their pKα â
values are determined as 26.1-29.3 in THF. They are thus probably the strongest known phosphorous-free organic bases both in solution and in the gas phase. Calculations help to determine the structural and electronic factors giving rise to the high basicity.
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MEDLINE
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En
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Angew Chem Int Ed Engl
Ano de publicação:
2014
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Article