Effect of ageing on tactile transduction processes.
Ageing Res Rev
; 13: 90-9, 2014 Jan.
Article
em En
| MEDLINE
| ID: mdl-24373814
ABSTRACT
With advancing age, a decline in the main sensory modalities including touch sensation and perception is well reported to occur. This review mainly outlines the peripheral components of touch perception highlighting ageing influences on morphological and functional features of cutaneous mechanical transducers and mechanosensitive ion channels, sensory innervation, neurotransmitters and even vascular system required to ensure efferent function of the afferent nerve fibres in the skin. This, in conjunction with effect of ageing on the skin per se and central nervous system, could explain the tactile deficit seen among the ageing population. We also discuss appropriate tools and experimental models available to study the age-related tactile decline.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Células Receptoras Sensoriais
/
Pele
/
Tato
/
Envelhecimento
/
Mecanotransdução Celular
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Ageing Res Rev
Assunto da revista:
GERIATRIA
Ano de publicação:
2014
Tipo de documento:
Article