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Effect of ageing on tactile transduction processes.
Decorps, Johanna; Saumet, Jean Louis; Sommer, Pascal; Sigaudo-Roussel, Dominique; Fromy, Berengere.
Afiliação
  • Decorps J; Laboratory of Tissue Biology and Therapeutic Engineering, Centre National de la Recherche Scientifique (CNRS) UMR 5305, Lyon, France; University of Lyon 1, UMR 5305, Lyon, France. Electronic address: johannadecorps@hotmail.com.
  • Saumet JL; Laboratory of Tissue Biology and Therapeutic Engineering, Centre National de la Recherche Scientifique (CNRS) UMR 5305, Lyon, France; University of Lyon 1, UMR 5305, Lyon, France. Electronic address: jlsaumet@gmail.com.
  • Sommer P; Laboratory of Tissue Biology and Therapeutic Engineering, Centre National de la Recherche Scientifique (CNRS) UMR 5305, Lyon, France; University of Lyon 1, UMR 5305, Lyon, France. Electronic address: p.sommer@ibcp.fr.
  • Sigaudo-Roussel D; Laboratory of Tissue Biology and Therapeutic Engineering, Centre National de la Recherche Scientifique (CNRS) UMR 5305, Lyon, France; University of Lyon 1, UMR 5305, Lyon, France. Electronic address: dominique.sigaudo-roussel@univ-lyon1.fr.
  • Fromy B; Laboratory of Tissue Biology and Therapeutic Engineering, Centre National de la Recherche Scientifique (CNRS) UMR 5305, Lyon, France; University of Lyon 1, UMR 5305, Lyon, France. Electronic address: berengere.fromy@univ-lyon1.fr.
Ageing Res Rev ; 13: 90-9, 2014 Jan.
Article em En | MEDLINE | ID: mdl-24373814
ABSTRACT
With advancing age, a decline in the main sensory modalities including touch sensation and perception is well reported to occur. This review mainly outlines the peripheral components of touch perception highlighting ageing influences on morphological and functional features of cutaneous mechanical transducers and mechanosensitive ion channels, sensory innervation, neurotransmitters and even vascular system required to ensure efferent function of the afferent nerve fibres in the skin. This, in conjunction with effect of ageing on the skin per se and central nervous system, could explain the tactile deficit seen among the ageing population. We also discuss appropriate tools and experimental models available to study the age-related tactile decline.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células Receptoras Sensoriais / Pele / Tato / Envelhecimento / Mecanotransdução Celular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Ageing Res Rev Assunto da revista: GERIATRIA Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Células Receptoras Sensoriais / Pele / Tato / Envelhecimento / Mecanotransdução Celular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Ageing Res Rev Assunto da revista: GERIATRIA Ano de publicação: 2014 Tipo de documento: Article