[Blueberry Muffin Baby and Langerhans' congenital cell histiocytosis]. / Histiocytose langerhansienne congénitale et « Blueberry Muffin Baby ¼
Ann Dermatol Venereol
; 141(2): 130-3, 2014 Feb.
Article
em Fr
| MEDLINE
| ID: mdl-24507207
ABSTRACT
BACKGROUND:
Blueberry Muffin Baby is a rare neonatal cutaneous syndrome for purpuric lesions reflective of extramedullary hematopoiesis. Many causes are known, examples are congenital infections, malignancy and hematologic disorders. Langerhans' cell histiocytosis is a clonal proliferation of dendritic histiocytes. This has very rarely been associated with a Blueberry Muffin Baby presentation. CASE REPORT We report the case of a newborn presenting with Blueberry Muffin Baby syndrome related to congenital Langherans' cell histiocytosis. At birth, he had multiple purpuric lesions on the trunk, limbs and face. Skin biopsy showed a dermal proliferation of histiocytes staining positive for S100 and CD1a. Chest and bone radiographs, and abdominal ultrasound were normal. Skin lesions have resolved in 8 weeks, the patient is in complete remission at 18 months of follow-up.DISCUSSION:
A Blueberry Muffin Baby syndrome may reveal neonatal Langerhans' histiocytosis.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Hematopoese Extramedular
/
Histiocitose de Células de Langerhans
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Newborn
Idioma:
Fr
Revista:
Ann Dermatol Venereol
Ano de publicação:
2014
Tipo de documento:
Article