Muscle-fat MRI: 1.5 Tesla and 3.0 Tesla versus histology.
Muscle Nerve
; 50(2): 170-6, 2014 Aug.
Article
em En
| MEDLINE
| ID: mdl-24677256
ABSTRACT
INTRODUCTION:
We evaluated muscle/fat fraction (MFF) accuracy and reliability measured with an MR imaging technique at 1.5 Tesla (T) and 3.0T scanner strengths, using biopsy as reference.METHODS:
MRI was performed on muscle samples from pig and rabbit species (n = 8) at 1.5T and 3.0T. A chemical shift based 2-point Dixon method was used, collecting in-phase and out-of-phase data for fat/water of muscle samples. Values were compared with MFFs calculated from histology.RESULTS:
No significant difference was found between 1.5T and 3.0T (P values = 0.41-0.96), or between histology and imaging (P = 0.83) for any muscle tested.CONCLUSIONS:
RESULTS suggest that a 2-point Dixon fat/water separation MRI technique may provide reliable quantification of MFFs at varying field strengths across different animal species, and consistency was established with biopsy. The results set a foundation for larger scale investigation of quantifying muscle fat in neuromuscular disorders.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
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Tecido Adiposo
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Músculo Esquelético
Limite:
Animals
Idioma:
En
Revista:
Muscle Nerve
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Estados Unidos