The brain-stomach connection.
Front Horm Res
; 42: 83-92, 2014.
Article
em En
| MEDLINE
| ID: mdl-24732927
ABSTRACT
The stomach-brain connection has been revealed to be one of the most promising targets in treating obesity. The stomach plays a key role in the homeostatic mechanism implicating stomach-brain communication regulated under neural and hormonal control. The present review explores specific topics related to gut-brain interactions focus on the stomach-brain connection through the different known systems implied in energy balance control as ghrelin, and nesfatin. Moreover, novel mechanisms for energy balance regulation involving gastric-brain communication are described including the role of the gastric intracellular mTOR/S6K1 pathway mediating the interaction among ghrelin, nesfatin and endocannabinoid gastric systems to modulate metabolism.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Encéfalo
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Leptina
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Metabolismo Energético
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Mucosa Gástrica
Limite:
Animals
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Humans
Idioma:
En
Revista:
Front Horm Res
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Espanha