Thiol modification by bioactivated polyphenols and its potential role in skin inflammation.
Biosci Biotechnol Biochem
; 78(6): 1067-70, 2014.
Article
em En
| MEDLINE
| ID: mdl-25036136
ABSTRACT
In the present study, we evaluated the modifying behavior of simple phenolic compounds on the sulfhydryl groups of glutathione and proteins. The catechol-type polyphenols, including protocatechuic acid, but neither the monophenols nor O-methylated catechol, can modify the sulfhydryl groups in a phenol oxidase-dependent manner. The possible involvement of polyphenol bioactivation in the enhancement of skin inflammation was also suggested.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Dermatopatias
/
Compostos de Sulfidrila
/
Polifenóis
Limite:
Animals
Idioma:
En
Revista:
Biosci Biotechnol Biochem
Assunto da revista:
BIOQUIMICA
/
BIOTECNOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Japão