Diabetes induces changes in KIF1A, KIF5B and dynein distribution in the rat retina: implications for axonal transport.

Baptista, Filipa I; Pinto, Maria J; Elvas, Filipe; Martins, Tiago; Almeida, Ramiro D; Ambrósio, António F

Baptista, Filipa I; Pinto, Maria J; Elvas, Filipe; Martins, Tiago; Almeida, Ramiro D; Ambrósio, António F.

Afiliação

Baptista FI; Centre of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal; Pharmacology and Experimental Therapeutics, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal.
Pinto MJ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal; PhD Programme in Experimental Biology and Biomedicine (PDBEB), Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.
Elvas F; Centre of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal; Pharmacology and Experimental Therapeutics, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal.
Martins T; Centre of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal; Pharmacology and Experimental Therapeutics, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal.
Almeida RD; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal.
Ambrósio AF; Centre of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal; Pharmacology and Experimental Therapeutics, IBILI, Faculty of Medicine, University of Coimbra, 3004-548 Coimbra, Portugal; CNC-Center for Neuroscience and Cell Biology, Univers

Exp Eye Res ; 127: 91-103, 2014 Oct.

Article em En | MEDLINE | ID: mdl-25064602

Assuntos

Transporte Axonal/fisiologia; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Tipo 1/metabolismo; Dineínas/metabolismo; Cinesinas/metabolismo; Neurônios Retinianos/metabolismo; Animais; Western Blotting; Células Cultivadas; Diabetes Mellitus Experimental/genética; Diabetes Mellitus Experimental/patologia; Diabetes Mellitus Tipo 1/genética; Diabetes Mellitus Tipo 1/patologia; Dineínas/genética; Técnica Indireta de Fluorescência para Anticorpo; Glucose/farmacologia; Hiperglicemia/metabolismo; Cinesinas/genética; Masculino; Manitol/farmacologia; Microscopia Confocal; RNA Mensageiro/genética; Ratos; Ratos Wistar; Neurônios Retinianos/efeitos dos fármacos; Neurônios Retinianos/patologia

Palavras-chave

axonal transport; diabetes; dynein; kinesin; retina

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Transporte Axonal / Cinesinas / Dineínas / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Neurônios Retinianos Limite: Animals Idioma: En Revista: Exp Eye Res Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Portugal

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