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Structure-based optimization of non-peptidic Cathepsin D inhibitors.
Grädler, Ulrich; Czodrowski, Paul; Tsaklakidis, Christos; Klein, Markus; Werkmann, Daniela; Lindemann, Sven; Maskos, Klaus; Leuthner, Birgitta.
Afiliação
  • Grädler U; Merck KGaA, Merck Serono Research, Small Molecule Platform, Frankfurter Str. 250, 64293 Darmstadt, Germany. Electronic address: ulrich.graedler@merckgroup.com.
  • Czodrowski P; Merck KGaA, Merck Serono Research, Small Molecule Platform, Frankfurter Str. 250, 64293 Darmstadt, Germany.
  • Tsaklakidis C; Merck KGaA, Merck Serono Research, Small Molecule Platform, Frankfurter Str. 250, 64293 Darmstadt, Germany.
  • Klein M; Merck KGaA, Merck Serono Research, Small Molecule Platform, Frankfurter Str. 250, 64293 Darmstadt, Germany.
  • Werkmann D; Merck KGaA, Merck Serono Research, Small Molecule Platform, Frankfurter Str. 250, 64293 Darmstadt, Germany.
  • Lindemann S; Merck KGaA, Merck Serono Research, Small Molecule Platform, Frankfurter Str. 250, 64293 Darmstadt, Germany.
  • Maskos K; Proteros Biostructures GmbH, Bunsenstrasse 7a, 82152 Martinsried, Germany.
  • Leuthner B; Merck KGaA, Merck Serono Research, Small Molecule Platform, Frankfurter Str. 250, 64293 Darmstadt, Germany.
Bioorg Med Chem Lett ; 24(17): 4141-50, 2014 Sep 01.
Article em En | MEDLINE | ID: mdl-25086681
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Inibidores de Proteases / Catepsina D Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Inibidores de Proteases / Catepsina D Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article