Your browser doesn't support javascript.
loading
Mutational analysis of Pneumocystis jirovecii dihydropteroate synthase and dihydrofolate reductase genes in HIV-infected patients in China.
Deng, Xilong; Zhuo, Li; Lan, Yun; Dai, Zhaoxia; Chen, Wan-shan; Cai, Weiping; Kovacs, Joseph A; Ma, Liang; Tang, Xiaoping.
Afiliação
  • Deng X; Intensive Care Unit, Guangzhou No. 8 People's Hospital, Guangzhou, Guangdong Province, China Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
  • Zhuo L; Department of Infectious Diseases, Guangzhou No. 8 People's Hospital, Guangzhou, Guangdong Province, China.
  • Lan Y; Department of Laboratory Medicine, Guangzhou No. 8 People's Hospital, Guangzhou, Guangdong Province, China.
  • Dai Z; Department of Infectious Diseases, Guangzhou No. 8 People's Hospital, Guangzhou, Guangdong Province, China.
  • Chen WS; Department of Laboratory Medicine, Guangzhou No. 8 People's Hospital, Guangzhou, Guangdong Province, China.
  • Cai W; Department of Infectious Diseases, Guangzhou No. 8 People's Hospital, Guangzhou, Guangdong Province, China.
  • Kovacs JA; Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
  • Ma L; Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
  • Tang X; Department of Infectious Diseases, Guangzhou No. 8 People's Hospital, Guangzhou, Guangdong Province, China xtang@21cn.com.
J Clin Microbiol ; 52(11): 4017-9, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25122865
ABSTRACT
We investigated Pneumocystis jirovecii dihydropteroate synthase (DHPS) and dihydrofolate reductase (DHFR) genes for mutations in 25 Chinese HIV-infected patients with P. jirovecii pneumonia. We identified DHPS mutations in 3 (12%) patients and DHFR mutations in 1 (4%) patient. The prevalence of DHPS and DHFR mutations in China remains low, as it does in other developing countries.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tetra-Hidrofolato Desidrogenase / Infecções por HIV / Pneumocystis carinii / Di-Hidropteroato Sintase / Mutação Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: J Clin Microbiol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tetra-Hidrofolato Desidrogenase / Infecções por HIV / Pneumocystis carinii / Di-Hidropteroato Sintase / Mutação Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: J Clin Microbiol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos