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A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease.
Holmes, Michael V; Frikke-Schmidt, Ruth; Melis, Daniela; Luben, Robert; Asselbergs, Folkert W; Boer, Jolanda M A; Cooper, Jackie; Palmen, Jutta; Horvat, Pia; Engmann, Jorgen; Li, Ka-Wah; Onland-Moret, N Charlotte; Hofker, Marten H; Kumari, Meena; Keating, Brendan J; Hubacek, Jaroslav A; Adamkova, Vera; Kubinova, Ruzena; Bobak, Martin; Khaw, Kay-Tee; Nordestgaard, Børge G; Wareham, Nick; Humphries, Steve E; Langenberg, Claudia; Tybjaerg-Hansen, Anne; Talmud, Philippa J.
Afiliação
  • Holmes MV; Department of Surgery, Division of Transplantation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Epidemiology & Public Health, University College London, London, UK. Electronic address: mvholmes@gmail.com.
  • Frikke-Schmidt R; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denma
  • Melis D; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK.
  • Luben R; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Asselbergs FW; Department of Cardiology, Division Heart & Lungs, University Medical Center, Utrecht, The Netherlands; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands; Institute of Cardiovascular Science, faculty of Population Health Sciences, University Coll
  • Boer JM; Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, PO Box 1, 3720 BA Bilthoven, The Netherlands.
  • Cooper J; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK.
  • Palmen J; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK.
  • Horvat P; Department of Epidemiology & Public Health, University College London, London, UK.
  • Engmann J; Department of Epidemiology & Public Health, University College London, London, UK.
  • Li KW; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK.
  • Onland-Moret NC; Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands.
  • Hofker MH; Department of Pediatrics, Molecular Genetics, University Medical Center Groningen and Groningen University, Groningen, The Netherlands.
  • Kumari M; Department of Epidemiology & Public Health, University College London, London, UK.
  • Keating BJ; Department of Surgery, Division of Transplantation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Hubacek JA; Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Videnska 1958/9, Prague 4, 14021, Czech Republic.
  • Adamkova V; Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Videnska 1958/9, Prague 4, 14021, Czech Republic.
  • Kubinova R; National Institute of Public Health, Srobarova 48, 10042 Prague, Czech Republic.
  • Bobak M; Department of Epidemiology & Public Health, University College London, London, UK.
  • Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Nordestgaard BG; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, Denmark; The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, D
  • Wareham N; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
  • Humphries SE; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK.
  • Langenberg C; Department of Epidemiology & Public Health, University College London, London, UK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, UK.
  • Tybjaerg-Hansen A; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, Denmark; The Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hosp
  • Talmud PJ; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK.
Atherosclerosis ; 237(1): 5-12, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25173947
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fumar / Doença das Coronárias / Apolipoproteína E4 / Genótipo Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Atherosclerosis Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fumar / Doença das Coronárias / Apolipoproteína E4 / Genótipo Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Atherosclerosis Ano de publicação: 2014 Tipo de documento: Article