Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas.

Barnes, Tammy M; Otero, Yolanda F; Elliott, Amicia D; Locke, Alicia D; Malabanan, Carlo M; Coldren, Anastasia G; Brissova, Marcela; Piston, David W; McGuinness, Owen P

Barnes, Tammy M; Otero, Yolanda F; Elliott, Amicia D; Locke, Alicia D; Malabanan, Carlo M; Coldren, Anastasia G; Brissova, Marcela; Piston, David W; McGuinness, Owen P.

Afiliação

Barnes TM; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Otero YF; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Elliott AD; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Locke AD; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Malabanan CM; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Coldren AG; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Brissova M; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Piston DW; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
McGuinness OP; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee owen.mcguinness@vanderbilt.edu.

Am J Physiol Endocrinol Metab ; 307(10): E896-905, 2014 Nov 15.

Article em En | MEDLINE | ID: mdl-25205821

Assuntos

Encéfalo/metabolismo; Células Secretoras de Glucagon/metabolismo; Glucagon/metabolismo; Interleucina-6/genética; Animais; Encéfalo/efeitos dos fármacos; Epinefrina/farmacologia; Glucagon/efeitos dos fármacos; Técnica Clamp de Glucose; Hipoglicemia/metabolismo; Interleucina-6/metabolismo; Ilhotas Pancreáticas/metabolismo; Lipopolissacarídeos/farmacologia; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Estresse Fisiológico; Simpatomiméticos/farmacologia

Palavras-chave

endotoxemia; glucagon; hypoglycemia; inflammation; interleukin-6

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Encéfalo / Glucagon / Interleucina-6 / Células Secretoras de Glucagon Limite: Animals Idioma: En Revista: Am J Physiol Endocrinol Metab Assunto da revista: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Ano de publicação: 2014 Tipo de documento: Article

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