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Impaired TLR4 and HIF expression in cystic fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro.
Chillappagari, Shashi; Venkatesan, Shalini; Garapati, Virajith; Mahavadi, Poornima; Munder, Antje; Seubert, Andreas; Sarode, Gaurav; Guenther, Andreas; Schmeck, Bernd T; Tümmler, Burkhard; Henke, Markus O.
Afiliação
  • Chillappagari S; Department of Medicine, Pulmonary Critical Care Philipps University, Marburg, Germany; Institute for Lung Research, Philipps-University, Marburg, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL);
  • Venkatesan S; Department of Internal Medicine, Justus-Liebig-University, Giessen, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL);
  • Garapati V; Department of Medicine, Pulmonary Critical Care Philipps University, Marburg, Germany; Institute for Lung Research, Philipps-University, Marburg, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL);
  • Mahavadi P; Department of Internal Medicine, Justus-Liebig-University, Giessen, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL);
  • Munder A; Clinical Research Group 'Molecular Pathology of Cystic Fibrosis and Pseudomonas Genomics', Clinic for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Germany;
  • Seubert A; Department of Chemistry-Biochemistry, Philipps University, Marburg, Germany;
  • Sarode G; Department of Medicine, Pulmonary Critical Care Philipps University, Marburg, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany;
  • Guenther A; Department of Internal Medicine, Justus-Liebig-University, Giessen, Germany; Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL);
  • Schmeck BT; Institute for Lung Research, Philipps-University, Marburg, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL);
  • Tümmler B; Clinical Research Group 'Molecular Pathology of Cystic Fibrosis and Pseudomonas Genomics', Clinic for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Germany;
  • Henke MO; Department of Medicine, Pulmonary Critical Care Philipps University, Marburg, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL); Pneumology, Asklepios Fachkliniken München-Gauting, Germany; Comprehensive Pneumology
Am J Physiol Lung Cell Mol Physiol ; 307(10): L791-9, 2014 Nov 15.
Article em En | MEDLINE | ID: mdl-25239913
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Brônquios / Regulação para Baixo / Mucosa Respiratória / Fibrose Cística / Células Epiteliais / Heme Oxigenase-1 / Subunidade alfa do Fator 1 Induzível por Hipóxia / Receptor 4 Toll-Like / Homeostase / Ferro Limite: Animals / Humans Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Brônquios / Regulação para Baixo / Mucosa Respiratória / Fibrose Cística / Células Epiteliais / Heme Oxigenase-1 / Subunidade alfa do Fator 1 Induzível por Hipóxia / Receptor 4 Toll-Like / Homeostase / Ferro Limite: Animals / Humans Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2014 Tipo de documento: Article