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DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells.
Pont, Lotte M E Berghauser; Naipal, Kishan; Kloezeman, Jenneke J; Venkatesan, Subramanian; van den Bent, Martin; van Gent, Dik C; Dirven, Clemens M F; Kanaar, Roland; Lamfers, Martine L M; Leenstra, Sieger.
Afiliação
  • Pont LM; Department of Neurosurgery, Brain Tumor Center, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.
  • Naipal K; Department of Genetics, Department Radiation Oncology, Cancer Genomics Netherlands, Erasmus MC Cancer Institute, PO Box 2040, 3000 CA Rotterdam, The Netherlands.
  • Kloezeman JJ; Department of Neurosurgery, Brain Tumor Center, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.
  • Venkatesan S; Department of Neurosurgery, Brain Tumor Center, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.
  • van den Bent M; Department of Neurology/Neuro-oncology, Brain Tumor Center, Erasmus MC Cancer Institute, Dr. Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.
  • van Gent DC; Department of Genetics, Department Radiation Oncology, Cancer Genomics Netherlands, Erasmus MC Cancer Institute, PO Box 2040, 3000 CA Rotterdam, The Netherlands.
  • Dirven CM; Department of Neurosurgery, Brain Tumor Center, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.
  • Kanaar R; Department of Genetics, Department Radiation Oncology, Cancer Genomics Netherlands, Erasmus MC Cancer Institute, PO Box 2040, 3000 CA Rotterdam, The Netherlands.
  • Lamfers ML; Department of Neurosurgery, Brain Tumor Center, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.
  • Leenstra S; Department of Neurosurgery, Brain Tumor Center, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands; Department of Neurosurgery, Elizabeth Medical Hospital, Tilburg, The Netherlands. Electronic address: s.leenstra@erasmusmc.nl.
Cancer Lett ; 356(2 Pt B): 525-35, 2015 Jan 28.
Article em En | MEDLINE | ID: mdl-25305451

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Radiossensibilizantes / Dano ao DNA / Apoptose / Glioblastoma / Proteínas Reguladoras de Apoptose / Inibidores de Histona Desacetilases / Ácidos Hidroxâmicos / Indóis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Lett Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Radiossensibilizantes / Dano ao DNA / Apoptose / Glioblastoma / Proteínas Reguladoras de Apoptose / Inibidores de Histona Desacetilases / Ácidos Hidroxâmicos / Indóis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Lett Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda