Utility of measuring (1,3)-ß-d-glucan in cerebrospinal fluid for diagnosis of fungal central nervous system infection.
J Clin Microbiol
; 53(1): 319-22, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-25378578
ABSTRACT
(1-3)-ß-d-Glucan (BDG) from cerebrospinal fluid (CSF) is a promising marker for diagnostic and prognostic aid of central nervous system (CNS) fungal infection, but its relationship to serum values has not been studied. Herein, we detected BDG from CSF at levels 2-fold lower than those in serum in patients without evidence of fungal disease but 25-fold higher than those in in serum in noncryptococcal CNS fungal infections. CSF BDG may be a useful biomarker in the evaluation of fungal CNS disease.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Biomarcadores
/
Infecções Fúngicas do Sistema Nervoso Central
/
Beta-Glucanas
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Clin Microbiol
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Estados Unidos