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Geroscience: linking aging to chronic disease.
Kennedy, Brian K; Berger, Shelley L; Brunet, Anne; Campisi, Judith; Cuervo, Ana Maria; Epel, Elissa S; Franceschi, Claudio; Lithgow, Gordon J; Morimoto, Richard I; Pessin, Jeffrey E; Rando, Thomas A; Richardson, Arlan; Schadt, Eric E; Wyss-Coray, Tony; Sierra, Felipe.
Afiliação
  • Kennedy BK; Buck Institute for Research on Aging, Novato, CA USA. Electronic address: bkennedy@buckinstitute.org.
  • Berger SL; Penn Epigenetics Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology and Department of Genetics and Department of Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Brunet A; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Glenn Center for the Biology of Aging, Stanford University, Stanford, CA 94305, USA.
  • Campisi J; Buck Institute for Research on Aging, Novato, CA USA; Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Cuervo AM; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Epel ES; Department of Psychiatry, School of Medicine, University of California, San Francisco, CA 94143, USA.
  • Franceschi C; IRCCS Institute of Neurological Sciences of Bologna, Bellaria Hospital, Bologna, Italy; C.I.G., Interdepartmental Center 'L. Galvani' for Integrated Studies on Bioinformatics, Biophysics, and Biocomplexity, University of Bologna, 3 Bologna, Italy; DIMES, Department of Experimental, Diagnostic and Sp
  • Lithgow GJ; Buck Institute for Research on Aging, Novato, CA USA.
  • Morimoto RI; Department of Biochemistry, Molecular Biology, and Cell Biology, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL 60208, USA.
  • Pessin JE; Department of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Rando TA; Glenn Center for the Biology of Aging, Stanford University, Stanford, CA 94305, USA; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Center for Tissue Regeneration, Repair and Restoration, Veterans Administration Palo Alto Health Ca
  • Richardson A; Donald W Reynolds Endowed Chair of Aging Research, Professor of Geriatric Medicine, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA; Oklahoma City VA Medical Center, Oklahoma City, OK 73104, USA.
  • Schadt EE; Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences and the Icahn Institute for Genomics and Multiscale Biology, New York, NY 10029, USA.
  • Wyss-Coray T; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA; Center for Tissue Regeneration, Repair and Restoration, Veterans Administration Palo Alto Health Care System, Palo Alto, CA 94304, USA.
  • Sierra F; Division of Aging Biology, National Institute on Aging, Bethesda, MD 20892, USA.
Cell ; 159(4): 709-13, 2014 Nov 06.
Article em En | MEDLINE | ID: mdl-25417146
ABSTRACT
Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches. Given that the elderly population is dramatically increasing and that aging is the greatest risk factor for a majority of chronic diseases driving both morbidity and mortality, it is critical to expand geroscience research directed at extending human healthspan.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Envelhecimento / Doença Crônica Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Envelhecimento / Doença Crônica Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Cell Ano de publicação: 2014 Tipo de documento: Article