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Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression.
Angiolilli, Chiara; Grabiec, Aleksander M; Ferguson, Bradley S; Ospelt, Caroline; Malvar Fernandez, Beatriz; van Es, Inge E; van Baarsen, Lisa G M; Gay, Steffen; McKinsey, Timothy A; Tak, Paul P; Baeten, Dominique L; Reedquist, Kris A.
Afiliação
  • Angiolilli C; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Grabiec AM; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Ferguson BS; Division of Cardiology, Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA.
  • Ospelt C; Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland.
  • Malvar Fernandez B; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • van Es IE; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • van Baarsen LG; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Gay S; Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland.
  • McKinsey TA; Division of Cardiology, Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA.
  • Tak PP; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands GlaxoSmithKline, Stevenage, UK Cambridge University, Cambridge, UK.
  • Baeten DL; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Reedquist KA; Department of Experimental Immunology and Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Ann Rheum Dis ; 75(2): 430-8, 2016 Feb.
Article em En | MEDLINE | ID: mdl-25452308

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Artrite Reumatoide / Membrana Sinovial / Citocinas / Fibroblastos / Histona Desacetilases Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Artrite Reumatoide / Membrana Sinovial / Citocinas / Fibroblastos / Histona Desacetilases Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Holanda