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Neuregulin 1 expression is a predictive biomarker for response to AV-203, an ERBB3 inhibitory antibody, in human tumor models.
Meetze, Kristan; Vincent, Sylvie; Tyler, Steven; Mazsa, Elizabeth K; Delpero, Andrea R; Bottega, Steve; McIntosh, Donna; Nicoletti, Richard; Winston, William M; Weiler, Solly; Feng, Bin; Gyuris, Jeno; Weng, Zhigang.
Afiliação
  • Meetze K; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Vincent S; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Tyler S; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Mazsa EK; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Delpero AR; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Bottega S; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • McIntosh D; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Nicoletti R; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Winston WM; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Weiler S; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Feng B; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Gyuris J; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts.
  • Weng Z; AVEO Pharmaceuticals, Inc., Cambridge, Massachusetts. zweng@aveooncology.com.
Clin Cancer Res ; 21(5): 1106-14, 2015 Mar 01.
Article em En | MEDLINE | ID: mdl-25542901
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Expressão Gênica / Receptor ErbB-3 / Neuregulina-1 / Anticorpos Monoclonais Humanizados / Neoplasias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Expressão Gênica / Receptor ErbB-3 / Neuregulina-1 / Anticorpos Monoclonais Humanizados / Neoplasias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article