A case of acute kidney injury from crystal nephropathy secondary to pomalidomide and levofloxacin use.
J Oncol Pharm Pract
; 22(2): 357-60, 2016 Apr.
Article
em En
| MEDLINE
| ID: mdl-25591868
Pomalidomide is an analog of thalidomide with immunomodulatory, anti-angiogenic, and anti-neoplastic activity indicated for the treatment of multiple myeloma refractory to at least two prior therapies. The incidence for renal failure was <5% in a single phase II study of pomalidomide and dexamethasone in patients with multiple myeloma that failed both lenalidomide and bortezomib therapy. We report a case suggesting crystal nephropathy as the mechanism for acute kidney injury in pomalidomide and fluoroquinolone use.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Talidomida
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Protocolos de Quimioterapia Combinada Antineoplásica
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Injúria Renal Aguda
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Levofloxacino
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
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Female
/
Humans
Idioma:
En
Revista:
J Oncol Pharm Pract
Assunto da revista:
FARMACIA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos