MicroRNA-141 inhibits tumor growth and metastasis in gastric cancer by directly targeting transcriptional co-activator with PDZ-binding motif, TAZ.

Zuo, Q-F; Zhang, R; Li, B-S; Zhao, Y-L; Zhuang, Y; Yu, T; Gong, L; Li, S; Xiao, B; Zou, Q-M

Zuo, Q-F; Zhang, R; Li, B-S; Zhao, Y-L; Zhuang, Y; Yu, T; Gong, L; Li, S; Xiao, B; Zou, Q-M.

Afiliação

Zuo QF; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.
Zhang R; Research and Service Center of Laboratory Medicine, ChengDu Military General Hospital, Chengdu 610083, PR China.
Li BS; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.
Zhao YL; General Surgery and Center of Minimally Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing 400038, PR China.
Zhuang Y; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.
Yu T; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.
Gong L; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.
Li S; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.
Xiao B; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.
Zou QM; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China.

Cell Death Dis ; 6: e1623, 2015 Jan 29.

Article em En | MEDLINE | ID: mdl-25633292

Assuntos

Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Neoplasias Pulmonares/secundário; MicroRNAs/metabolismo; Neoplasias Gástricas/genética; Neoplasias Gástricas/patologia; Adulto; Idoso; Animais; Sequência de Bases; Movimento Celular; Proliferação de Células; Regulação para Baixo; Feminino; Regulação Neoplásica da Expressão Gênica; Humanos; Masculino; Camundongos Endogâmicos BALB C; Camundongos Nus; MicroRNAs/genética; Pessoa de Meia-Idade; Dados de Sequência Molecular; Invasividade Neoplásica; Transativadores; Fatores de Transcrição; Proteínas com Motivo de Ligação a PDZ com Coativador Transcricional; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Gástricas / MicroRNAs / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Death Dis Ano de publicação: 2015 Tipo de documento: Article

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