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High-affinity accumulation of a maytansinoid in cells via weak tubulin interaction.
Goldmacher, Victor S; Audette, Charlene A; Guan, Yinghua; Sidhom, Eriene-Heidi; Shah, Jagesh V; Whiteman, Kathleen R; Kovtun, Yelena V.
Afiliação
  • Goldmacher VS; Department of Cell Biology, ImmunoGen, Inc., Waltham, Massachusetts, United States of America.
  • Audette CA; Department of Cell Biology, ImmunoGen, Inc., Waltham, Massachusetts, United States of America.
  • Guan Y; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America; Renal Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
  • Sidhom EH; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America; Renal Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
  • Shah JV; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America; Renal Division, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
  • Whiteman KR; Department of Cell Biology, ImmunoGen, Inc., Waltham, Massachusetts, United States of America.
  • Kovtun YV; Department of Cell Biology, ImmunoGen, Inc., Waltham, Massachusetts, United States of America.
PLoS One ; 10(2): e0117523, 2015.
Article em En | MEDLINE | ID: mdl-25671541
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Maitansina Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Maitansina Limite: Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos