[Screening and identification of forensic molecular markers of injury using MALDI-TOF-MS imaging mass spectrometry].
Fa Yi Xue Za Zhi
; 30(5): 367-70, 2014 Oct.
Article
em Zh
| MEDLINE
| ID: mdl-25735076
ABSTRACT
There are many deficiencies in forensic traumatic molecular markers detected by the techniques of traditional immunohistology and molecular biology, because these markers are isolated and obscure of the mechanism of interaction. The imaging mass spectrometry (IMS) is more suitable for the forensic molecular markers using function of screening, analysis and graphical representation. In this paper, the techniques and the latest research in screening and identification of typical molecular markers by IMS based on matrix-assisted laser adsorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) are reviewed. And its application values in forensic injury are discussed.
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Bases de dados:
MEDLINE
Assunto principal:
Biomarcadores
/
Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
Zh
Revista:
Fa Yi Xue Za Zhi
Assunto da revista:
JURISPRUDENCIA
Ano de publicação:
2014
Tipo de documento:
Article