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A recent bottleneck of Y chromosome diversity coincides with a global change in culture.
Karmin, Monika; Saag, Lauri; Vicente, Mário; Wilson Sayres, Melissa A; Järve, Mari; Talas, Ulvi Gerst; Rootsi, Siiri; Ilumäe, Anne-Mai; Mägi, Reedik; Mitt, Mario; Pagani, Luca; Puurand, Tarmo; Faltyskova, Zuzana; Clemente, Florian; Cardona, Alexia; Metspalu, Ene; Sahakyan, Hovhannes; Yunusbayev, Bayazit; Hudjashov, Georgi; DeGiorgio, Michael; Loogväli, Eva-Liis; Eichstaedt, Christina; Eelmets, Mikk; Chaubey, Gyaneshwer; Tambets, Kristiina; Litvinov, Sergei; Mormina, Maru; Xue, Yali; Ayub, Qasim; Zoraqi, Grigor; Korneliussen, Thorfinn Sand; Akhatova, Farida; Lachance, Joseph; Tishkoff, Sarah; Momynaliev, Kuvat; Ricaut, François-Xavier; Kusuma, Pradiptajati; Razafindrazaka, Harilanto; Pierron, Denis; Cox, Murray P; Sultana, Gazi Nurun Nahar; Willerslev, Rane; Muller, Craig; Westaway, Michael; Lambert, David; Skaro, Vedrana; Kovacevic, Lejla; Turdikulova, Shahlo; Dalimova, Dilbar; Khusainova, Rita.
Afiliação
  • Karmin M; Estonian Biocentre, Tartu, 51010, Estonia; Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia; tk331@cam.ac.uk monika.karmin@gmail.com.
  • Saag L; Estonian Biocentre, Tartu, 51010, Estonia; Department of Botany, Institute of Ecology and Earth Sciences, University of Tartu, Tartu, 51010, Estonia;
  • Vicente M; Division of Biological Anthropology, University of Cambridge, Cambridge, CB2 1QH, United Kingdom;
  • Wilson Sayres MA; Department of Integrative Biology, University of California Berkeley, Berkeley, California 94720, USA; School of Life Sciences and The Biodesign Institute, Tempe, Arizona 85287-5001, USA;
  • Järve M; Estonian Biocentre, Tartu, 51010, Estonia;
  • Talas UG; Department of Bioinformatics, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia;
  • Rootsi S; Estonian Biocentre, Tartu, 51010, Estonia;
  • Ilumäe AM; Estonian Biocentre, Tartu, 51010, Estonia; Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia;
  • Mägi R; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia;
  • Mitt M; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia;
  • Pagani L; Division of Biological Anthropology, University of Cambridge, Cambridge, CB2 1QH, United Kingdom;
  • Puurand T; Department of Bioinformatics, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia;
  • Faltyskova Z; Division of Biological Anthropology, University of Cambridge, Cambridge, CB2 1QH, United Kingdom;
  • Clemente F; Division of Biological Anthropology, University of Cambridge, Cambridge, CB2 1QH, United Kingdom;
  • Cardona A; Division of Biological Anthropology, University of Cambridge, Cambridge, CB2 1QH, United Kingdom;
  • Metspalu E; Estonian Biocentre, Tartu, 51010, Estonia; Department of Evolutionary Biology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia;
  • Sahakyan H; Estonian Biocentre, Tartu, 51010, Estonia; Laboratory of Ethnogenomics, Institute of Molecular Biology, National Academy of Sciences, Yerevan, 0014, Armenia;
  • Yunusbayev B; Estonian Biocentre, Tartu, 51010, Estonia; Institute of Biochemistry and Genetics, Ufa Scientific Center of the Russian Academy of Sciences, Ufa, 450054, Russia;
  • Hudjashov G; Estonian Biocentre, Tartu, 51010, Estonia; Department of Psychology, University of Auckland, Auckland, 1142, New Zealand;
  • DeGiorgio M; Department of Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA;
  • Loogväli EL; Estonian Biocentre, Tartu, 51010, Estonia;
  • Eichstaedt C; Division of Biological Anthropology, University of Cambridge, Cambridge, CB2 1QH, United Kingdom;
  • Eelmets M; Estonian Biocentre, Tartu, 51010, Estonia; Department of Bioinformatics, Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia;
  • Chaubey G; Estonian Biocentre, Tartu, 51010, Estonia;
  • Tambets K; Estonian Biocentre, Tartu, 51010, Estonia;
  • Litvinov S; Estonian Biocentre, Tartu, 51010, Estonia; Institute of Biochemistry and Genetics, Ufa Scientific Center of the Russian Academy of Sciences, Ufa, 450054, Russia;
  • Mormina M; Department of Applied Social Sciences, University of Winchester, Winchester, SO22 4NR, United Kingdom;
  • Xue Y; The Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, United Kingdom;
  • Ayub Q; The Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, United Kingdom;
  • Zoraqi G; Center of Molecular Diagnosis and Genetic Research, University Hospital of Obstetrics and Gynecology, Tirana, ALB1005, Albania;
  • Korneliussen TS; Department of Integrative Biology, University of California Berkeley, Berkeley, California 94720, USA; Center for GeoGenetics, University of Copenhagen, Copenhagen, DK-1350, Denmark;
  • Akhatova F; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, 450074, Russia; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, 420008, Russia;
  • Lachance J; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6145, USA; School of Biology, Georgia Institute of Technology, Atlanta, 30332, Georgia, USA;
  • Tishkoff S; Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6145, USA; Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6313, USA;
  • Momynaliev K; DNcode Laboratories, Moscow, 119992, Russia;
  • Ricaut FX; Evolutionary Medicine Group, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse, Centre National de la Recherche Scientifique, Université de Toulouse 3, Toulouse, 31073, France;
  • Kusuma P; Evolutionary Medicine Group, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse, Centre National de la Recherche Scientifique, Université de Toulouse 3, Toulouse, 31073, France; Eijkman Institute for Molecular Biology, Jakarta, 10430, Indonesia;
  • Razafindrazaka H; Evolutionary Medicine Group, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse, Centre National de la Recherche Scientifique, Université de Toulouse 3, Toulouse, 31073, France;
  • Pierron D; Evolutionary Medicine Group, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse, Centre National de la Recherche Scientifique, Université de Toulouse 3, Toulouse, 31073, France;
  • Cox MP; Statistics and Bioinformatics Group, Institute of Fundamental Sciences, Massey University, Palmerston North, 4442, New Zealand;
  • Sultana GN; Centre for Advanced Research in Sciences (CARS), DNA Sequencing Research Laboratory, University of Dhaka, Dhaka, Dhaka-1000, Bangladesh;
  • Willerslev R; Arctic Research Centre, Aarhus University, Aarhus, DK-8000, Denmark;
  • Muller C; Center for GeoGenetics, University of Copenhagen, Copenhagen, DK-1350, Denmark;
  • Westaway M; Environmental Futures Research Institute, Griffith University, Nathan, 4111, Australia;
  • Lambert D; Environmental Futures Research Institute, Griffith University, Nathan, 4111, Australia;
  • Skaro V; Genos, DNA Laboratory, Zagreb, 10000, Croatia; University of Osijek, Medical School, Osijek, 31000, Croatia;
  • Kovacevic L; Centogene AG, Rostock, 18057, Germany;
  • Turdikulova S; Institute of Bioorganic Chemistry, Academy of Science, Tashkent, 100143, Uzbekistan;
  • Dalimova D; Institute of Bioorganic Chemistry, Academy of Science, Tashkent, 100143, Uzbekistan;
  • Khusainova R; Institute of Biochemistry and Genetics, Ufa Scientific Center of the Russian Academy of Sciences, Ufa, 450054, Russia; Department of Genetics and Fundamental Medicine, Bashkir State University, Ufa, 450074, Russia;
Genome Res ; 25(4): 459-66, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25770088
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192-307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47-52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Evolução Molecular / Cromossomos Humanos Y / Grupos Raciais Limite: Humans / Male Idioma: En Revista: Genome Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Evolução Molecular / Cromossomos Humanos Y / Grupos Raciais Limite: Humans / Male Idioma: En Revista: Genome Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2015 Tipo de documento: Article