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The natural, peptaibolic peptide SPF-5506-A4 adopts a ß-bend spiral structure, shows low hemolytic activity and targets membranes through formation of large pores.
Christoffersen, Heidi F; Hansen, Sara K; Vad, Brian S; Nielsen, Erik H; Nielsen, Jakob T; Vosegaard, Thomas; Skrydstrup, Troels; Otzen, Daniel E.
Afiliação
  • Christoffersen HF; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark.
  • Hansen SK; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark.
  • Vad BS; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark.
  • Nielsen EH; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark.
  • Nielsen JT; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark.
  • Vosegaard T; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark. Electronic address: tv@chem.au.dk.
  • Skrydstrup T; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark. Electronic address: ts@inano.au.dk.
  • Otzen DE; Center for Insoluble Protein Structures (inSPIN), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark. Electronic address: dao@inano.au.dk.
Biochim Biophys Acta ; 1854(8): 882-9, 2015 Aug.
Article em En | MEDLINE | ID: mdl-25796141
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Oligopeptídeos / Permeabilidade da Membrana Celular / Membrana Eritrocítica / Modelos Químicos Limite: Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Oligopeptídeos / Permeabilidade da Membrana Celular / Membrana Eritrocítica / Modelos Químicos Limite: Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Dinamarca