Mechanoresponsive, omni-directional and local matrix-degrading actin protrusions in human mesenchymal stem cells microencapsulated in a 3D collagen matrix.

Ho, Fu Chak; Zhang, Wei; Li, Yuk Yin; Chan, Barbara Pui

Ho, Fu Chak; Zhang, Wei; Li, Yuk Yin; Chan, Barbara Pui.

Afiliação

Ho FC; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Zhang W; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Li YY; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region.
Chan BP; Tissue Engineering Laboratory, Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region. Electronic address: bpchan@hku.hk.

Biomaterials ; 53: 392-405, 2015.

Article em En | MEDLINE | ID: mdl-25890737

Assuntos

Colágeno/administração & dosagem; Composição de Medicamentos; Matriz Extracelular/metabolismo; Células-Tronco Mesenquimais/citologia; Células Cultivadas; Humanos; Células-Tronco Mesenquimais/metabolismo; Transdução de Sinais; Proteína cdc42 de Ligação ao GTP/metabolismo

Palavras-chave

Actin protrusions; Cellmatrix interface; Collagen microencapsulation; Human mesenchymal stem cells; Mechanopodia; Mechanoresponsive

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Colágeno / Composição de Medicamentos / Matriz Extracelular / Células-Tronco Mesenquimais Limite: Humans Idioma: En Revista: Biomaterials Ano de publicação: 2015 Tipo de documento: Article

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