Prenatal Supplementation with Docosahexaenoic Acid Has No Effect on Growth through 60 Months of Age.
J Nutr
; 145(6): 1330-4, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25926416
ABSTRACT
BACKGROUND:
Prenatal supplementation with docosahexaenoic acid (DHA) has been shown to increase birth size, but it is unclear whether these differences translate into improved postnatal growth.OBJECTIVE:
We assessed the effect of prenatal supplementation with DHA on offspring weight, length, and body mass index (BMI) through 60 mo of age.METHODS:
We examined growth patterns (height, weight, and BMI) in a cohort of 802 Mexican children whose mothers participated in a randomized, controlled trial of daily supplementation with 400 mg/d of DHA or a placebo from week 18-22 of gestation through delivery, with the use of a longitudinal multilevel model of growth.RESULTS:
Overall, means ± SDs of height-, weight-, and BMI-for-age z scores relative to WHO growth standards at 60 mo were -0.49 ± 0.91, -1.15 ± 1.07 and 0.13 ± 1.11, respectively. There were no significant differences by treatment group (all P > 0.05) for height, weight, or BMI at any age through 60 mo. Similarly, DHA did not affect the average growth or the trajectories for these measures through 60 mo.CONCLUSION:
Prenatal DHA supplementation did not affect height, weight, or BMI through 60 mo of age. This trial was registered at clinicaltrials.gov as NCT00646360.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Cuidado Pré-Natal
/
Ácidos Docosa-Hexaenoicos
/
Suplementos Nutricionais
Tipo de estudo:
Clinical_trials
/
Guideline
/
Prognostic_studies
Limite:
Adult
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Child, preschool
/
Female
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Humans
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Infant
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Male
País/Região como assunto:
Mexico
Idioma:
En
Revista:
J Nutr
Ano de publicação:
2015
Tipo de documento:
Article