Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis.

Hannan, Thomas J; Roberts, Pacita L; Riehl, Terrence E; van der Post, Sjoerd; Binkley, Jana M; Schwartz, Drew J; Miyoshi, Hiroyuki; Mack, Matthias; Schwendener, Reto A; Hooton, Thomas M; Stappenbeck, Thaddeus S; Hansson, Gunnar C; Stenson, William F; Colonna, Marco; Stapleton, Ann E; Hultgren, Scott J

Hannan, Thomas J; Roberts, Pacita L; Riehl, Terrence E; van der Post, Sjoerd; Binkley, Jana M; Schwartz, Drew J; Miyoshi, Hiroyuki; Mack, Matthias; Schwendener, Reto A; Hooton, Thomas M; Stappenbeck, Thaddeus S; Hansson, Gunnar C; Stenson, William F; Colonna, Marco; Stapleton, Ann E; Hultgren, Scott J.

Afiliação

Hannan TJ; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA ; Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Roberts PL; Division of Allergy & Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Riehl TE; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
van der Post S; Department of Medical Biochemistry, University of Gothenburg, 40530 Gothenburg, Sweden.
Binkley JM; Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Schwartz DJ; Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.
Miyoshi H; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Mack M; Department of Internal Medicine, University of Regensburg, 93053 Regensburg, Germany.
Schwendener RA; Institute of Molecular Cancer Research, University of Zurich, 8091 Zurich, Switzerland.
Hooton TM; Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Stappenbeck TS; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Hansson GC; Department of Medical Biochemistry, University of Gothenburg, 40530 Gothenburg, Sweden.
Stenson WF; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Colonna M; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Stapleton AE; Division of Allergy & Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Hultgren SJ; Department of Molecular Microbiology and Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110, USA.

EBioMedicine ; 1(1): 46-57, 2014 Nov.

Article em En | MEDLINE | ID: mdl-26125048

Palavras-chave

ASB, asymptomatic bacteriuria; CD, clusters of differentiation; COX, cyclooxygenase; COX-2; Chronic infection; G-CSF or CSF3, granulocyte colony-stimulating factor; GRO-α or CXCL1, growth-regulated alpha protein; IBC, intracellular bacterial community; IL-8 or CXCL8, interleukin-8; Immunomodulatory therapy; Immunopathology; M-CSF or CSF1, macrophage colony-stimulating factor; MAb, monoclonal antibody; MCP-1 or CCL2, monocyte chemotactic protein 1; Mucosal immunology; NSAID, non-steroidal anti-inflammatory drug; UPEC; UPEC, uropathogenic E. coli; UTI, recurrent infection; UTI, urinary tract infection; Urinary tract infection; Uropathogenic E. coli; rUTI, recurrent urinary tract infection

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Texto completo: 1 Bases de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: EBioMedicine Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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