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Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients.
Chen, Cai; Bartenhagen, Christoph; Gombert, Michael; Okpanyi, Vera; Binder, Vera; Röttgers, Silja; Bradtke, Jutta; Teigler-Schlegel, Andrea; Harbott, Jochen; Ginzel, Sebastian; Thiele, Ralf; Husemann, Peter; Krell, Pina F I; Borkhardt, Arndt; Dugas, Martin; Hu, Jianda; Fischer, Ute.
Afiliação
  • Chen C; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany; Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China.
  • Bartenhagen C; Institute of Medical Informatics, University of Münster, Münster, Germany.
  • Gombert M; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Okpanyi V; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Binder V; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Röttgers S; Oncogenetic Laboratory, Department of Pediatric Hematology and Oncology, Justus Liebig University, Giessen, Germany.
  • Bradtke J; Oncogenetic Laboratory, Department of Pediatric Hematology and Oncology, Justus Liebig University, Giessen, Germany.
  • Teigler-Schlegel A; Oncogenetic Laboratory, Department of Pediatric Hematology and Oncology, Justus Liebig University, Giessen, Germany.
  • Harbott J; Oncogenetic Laboratory, Department of Pediatric Hematology and Oncology, Justus Liebig University, Giessen, Germany.
  • Ginzel S; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany; Department of Computer Science, Bonn-Rhine-Sieg University of Applied Sciences, Sankt Augustin, Germany.
  • Thiele R; Department of Computer Science, Bonn-Rhine-Sieg University of Applied Sciences, Sankt Augustin, Germany.
  • Husemann P; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Krell PF; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Borkhardt A; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
  • Dugas M; Institute of Medical Informatics, University of Münster, Münster, Germany.
  • Hu J; Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China. Electronic address: jdhu@medmail.com.cn.
  • Fischer U; Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany. Electronic address: ute.fischer@med.uni-duesseldorf.de.
Leuk Res ; 39(9): 990-1001, 2015 Sep.
Article em En | MEDLINE | ID: mdl-26189108
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fatores de Transcrição / Regulação Leucêmica da Expressão Gênica / Proteínas Proto-Oncogênicas / Epigênese Genética / Proteínas Reguladoras de Apoptose / Leucemia-Linfoma Linfoblástico de Células Precursoras / Mutação Tipo de estudo: Etiology_studies Limite: Child, preschool / Female / Humans / Male Idioma: En Revista: Leuk Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fatores de Transcrição / Regulação Leucêmica da Expressão Gênica / Proteínas Proto-Oncogênicas / Epigênese Genética / Proteínas Reguladoras de Apoptose / Leucemia-Linfoma Linfoblástico de Células Precursoras / Mutação Tipo de estudo: Etiology_studies Limite: Child, preschool / Female / Humans / Male Idioma: En Revista: Leuk Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China