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Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT1 F receptor agonists: Evolution from bicyclic to monocyclic cores.
Zhang, Deyi; Blanco, Maria-Jesus; Ying, Bai-Ping; Kohlman, Daniel; Liang, Sidney X; Victor, Frantz; Chen, Qi; Krushinski, Joseph; Filla, Sandra A; Hudziak, Kevin J; Mathes, Brian M; Cohen, Michael P; Zacherl, DeAnna; Nelson, David L G; Wainscott, David B; Nutter, Suzanne E; Gough, Wendy H; Schaus, John M; Xu, Yao-Chang.
Afiliação
  • Zhang D; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Blanco MJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States. Electronic address: blanco_maria@lilly.com.
  • Ying BP; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Kohlman D; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Liang SX; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Victor F; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Chen Q; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Krushinski J; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Filla SA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Hudziak KJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Mathes BM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Cohen MP; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Zacherl D; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Nelson DL; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Wainscott DB; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Nutter SE; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Gough WH; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Schaus JM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
  • Xu YC; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States.
Bioorg Med Chem Lett ; 25(19): 4337-41, 2015 Oct 01.
Article em En | MEDLINE | ID: mdl-26271587
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Piperidinas / Benzamidas / Receptores 5-HT1 de Serotonina / Descoberta de Drogas / Agonistas do Receptor 5-HT1 de Serotonina Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Piperidinas / Benzamidas / Receptores 5-HT1 de Serotonina / Descoberta de Drogas / Agonistas do Receptor 5-HT1 de Serotonina Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos