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Hospitalisation rates and associated factors in community-based cohorts of HIV-infected and -uninfected gay and bisexual men.
Moore, C L; Grulich, A E; Prestage, G; Gidding, H F; Jin, F; Mao, L; Petoumenos, K; Zablotska, I B; Poynten, I M; Law, M G; Amin, J.
Afiliação
  • Moore CL; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
  • Grulich AE; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
  • Prestage G; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
  • Gidding HF; Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Vic., Australia.
  • Jin F; School of Public Health and Community Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Mao L; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
  • Petoumenos K; Centre for Social Research in Health, University of New South Wales, Sydney, NSW, Australia.
  • Zablotska IB; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
  • Poynten IM; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
  • Law MG; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
  • Amin J; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
HIV Med ; 17(5): 327-39, 2016 May.
Article em En | MEDLINE | ID: mdl-26344061
OBJECTIVES: There is evidence that HIV-positive patients are suffering from a greater burden of morbidity as they age due to nonAIDS-related complications. To date it has been difficult to determine what part of this excess risk is due to the health effects of HIV, its treatment or to lifestyle factors common to gay and bisexual men (GBM). We calculated overall and cause-specific hospitalisation rates and risk factors for hospitalisations in HIV-negative and HIV-positive cohorts of GBM and compare these with rates in the general male population. METHODS: We conducted a record linkage study, linking two cohorts of HIV-negative (n = 1325) and HIV-positive (n = 557) GBM recruited in Sydney, New South Wales (NSW), Australia with the NSW hospital discharge data register. We compared rates of hospitalisation in the two cohorts and risk factors for hospitalisation using random-effects Poisson regression methods. Hospitalisation rates for each cohort were further compared with those in the general male population using indirect standardisation. RESULTS: We observed 2032 hospitalisations in the HIV-negative cohort during 13,016 person-years (PYs) [crude rate: 15.6/100 PYs (95% CI: 14.9-16.3)] and 2130 hospitalisations in the HIV-positive cohort during 5571 PYs [crude rate: 38.2/100 PYs (95% CI: 36.6-39.9)]. HIV-positive individuals had an increased risk of hospitalisation compared with the HIV-negative individuals [adjusted-IRR: 2.34 (95% CI: 1.91-2.86)] and the general population [SHR: 1.45 (95% CI: 1.33-1.59)]. Hospitalisation rates were lower in the HIV-negative cohort compared with the general population [SHR: 0.72 (95% CI: 0.67-0.78)]. The primary causes of hospitalisation differed between groups. CONCLUSIONS: HIV-positive GBM continue to experience excess morbidity compared with HIV-negative GBM men and the general population. HIV-negative GBM had lower morbidity compared with the general male population suggesting that GBM identity does not confer excess risk.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Bissexualidade / Infecções por HIV / Homossexualidade Masculina / Hospitalização Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans / Male / Middle aged País/Região como assunto: Oceania Idioma: En Revista: HIV Med Assunto da revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Austrália

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Bissexualidade / Infecções por HIV / Homossexualidade Masculina / Hospitalização Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans / Male / Middle aged País/Região como assunto: Oceania Idioma: En Revista: HIV Med Assunto da revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Austrália