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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
Van Allen, Eliezer M; Miao, Diana; Schilling, Bastian; Shukla, Sachet A; Blank, Christian; Zimmer, Lisa; Sucker, Antje; Hillen, Uwe; Foppen, Marnix H Geukes; Goldinger, Simone M; Utikal, Jochen; Hassel, Jessica C; Weide, Benjamin; Kaehler, Katharina C; Loquai, Carmen; Mohr, Peter; Gutzmer, Ralf; Dummer, Reinhard; Gabriel, Stacey; Wu, Catherine J; Schadendorf, Dirk; Garraway, Levi A.
Afiliação
  • Van Allen EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Miao D; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Schilling B; Center for Cancer Precision Medicine, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Shukla SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Blank C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Zimmer L; Department of Dermatology, University Hospital, University Duisburg-Essen, 45147 Essen, Germany.
  • Sucker A; German Cancer Consortium (DKTK), 69121 Heidelberg, Germany.
  • Hillen U; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Foppen MHG; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Goldinger SM; Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
  • Utikal J; Department of Dermatology, University Hospital, University Duisburg-Essen, 45147 Essen, Germany.
  • Hassel JC; German Cancer Consortium (DKTK), 69121 Heidelberg, Germany.
  • Weide B; Department of Dermatology, University Hospital, University Duisburg-Essen, 45147 Essen, Germany.
  • Kaehler KC; German Cancer Consortium (DKTK), 69121 Heidelberg, Germany.
  • Loquai C; Department of Dermatology, University Hospital, University Duisburg-Essen, 45147 Essen, Germany.
  • Mohr P; German Cancer Consortium (DKTK), 69121 Heidelberg, Germany.
  • Gutzmer R; Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
  • Dummer R; Department of Dermatology, University Hospital Zurich, 8091 Zurich, Switzerland.
  • Gabriel S; German Cancer Consortium (DKTK), 69121 Heidelberg, Germany.
  • Wu CJ; Skin Cancer Unit, German Cancer Research Center(DKTK), 69121 Heidelberg, Germany.
  • Schadendorf D; Department of Dermatology, Venerology, and Allergology, University Medical Center, Ruprecht-Karls University of Heidelberg, 68167 Mannheim, Germany.
  • Garraway LA; Department of Dermatology, University Hospital, Ruprecht-Karls University of Heidelberg, 69120 Heidelberg, Germany.
Science ; 350(6257): 207-211, 2015 Oct 09.
Article em En | MEDLINE | ID: mdl-26359337
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Biomarcadores Farmacológicos / Antígeno CTLA-4 / Melanoma / Anticorpos Monoclonais / Antígenos de Neoplasias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Science Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Biomarcadores Farmacológicos / Antígeno CTLA-4 / Melanoma / Anticorpos Monoclonais / Antígenos de Neoplasias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Science Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos