Structural Insights into mitochondrial antiviral signaling protein (MAVS)-tumor necrosis factor receptor-associated factor 6 (TRAF6) signaling.

Shi, Zhubing; Zhang, Zhen; Zhang, Zhenzhen; Wang, Yanyan; Li, Chuanchuan; Wang, Xin; He, Feng; Sun, Lina; Jiao, Shi; Shi, Weiyang; Zhou, Zhaocai

Shi, Zhubing; Zhang, Zhen; Zhang, Zhenzhen; Wang, Yanyan; Li, Chuanchuan; Wang, Xin; He, Feng; Sun, Lina; Jiao, Shi; Shi, Weiyang; Zhou, Zhaocai.

Afiliação

Shi Z; From the School of Life Sciences and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, China, the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 20
Zhang Z; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and.
Zhang Z; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and.
Wang Y; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and.
Li C; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and.
Wang X; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and.
He F; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and.
Sun L; Qingdao Binhai University, Qingdao, Shandong 266555, China.
Jiao S; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and.
Shi W; From the School of Life Sciences and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, China, wshi@tongji.edu.cn.
Zhou Z; the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, State Key Laboratory of Cell Biology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, and zczhou@sibcb.ac.cn.

J Biol Chem ; 290(44): 26811-20, 2015 Oct 30.

Article em En | MEDLINE | ID: mdl-26385923

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/química; Fibroblastos/metabolismo; Interações Hospedeiro-Patógeno/genética; Mitocôndrias/metabolismo; Proteínas Recombinantes de Fusão/química; Fator 6 Associado a Receptor de TNF/química; Proteínas Adaptadoras de Transdução de Sinal/genética; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Sequência de Aminoácidos; Animais; Cristalografia por Raios X; Escherichia coli/genética; Escherichia coli/metabolismo; Fibroblastos/virologia; Expressão Gênica; Genes Reporter; Células HEK293; Humanos; Luciferases/genética; Luciferases/metabolismo; Camundongos; Camundongos Knockout; Mitocôndrias/virologia; Dados de Sequência Molecular; Mutação; Domínios e Motivos de Interação entre Proteínas; Estrutura Secundária de Proteína; Proteínas Recombinantes de Fusão/genética; Proteínas Recombinantes de Fusão/metabolismo; Vírus Sendai/fisiologia; Alinhamento de Sequência; Transdução de Sinais; Fator 6 Associado a Receptor de TNF/genética; Fator 6 Associado a Receptor de TNF/metabolismo

Palavras-chave

Antiviral signaling; MAVS; TNF receptor associated factor (TRAF); TRAF6; crystal structure; innate immunity; protein-protein interaction; signal transduction

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Proteínas Adaptadoras de Transdução de Sinal / Fator 6 Associado a Receptor de TNF / Interações Hospedeiro-Patógeno / Fibroblastos / Mitocôndrias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article

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