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Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Ke, Yazi D; van Hummel, Annika; Stevens, Claire H; Gladbach, Amadeus; Ippati, Stefania; Bi, Mian; Lee, Wei S; Krüger, Sarah; van der Hoven, Julia; Volkerling, Alexander; Bongers, Andre; Halliday, Glenda; Haass, Nikolas K; Kiernan, Matthew; Delerue, Fabien; Ittner, Lars M.
Afiliação
  • Ke YD; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • van Hummel A; Motor Neuron Disease Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Stevens CH; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Gladbach A; Motor Neuron Disease Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Ippati S; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Bi M; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Lee WS; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Krüger S; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • van der Hoven J; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Volkerling A; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Bongers A; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Halliday G; Dementia Research Unit, Department of Anatomy, Faculty of Medicine, School of Medical Sciences, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Haass NK; Biological Resources Imaging Laboratory, Mark Wainwright Analytical Centre, UNSW Australia, Sydney, NSW, 2052, Australia.
  • Kiernan M; Neuroscience Research Australia, Sydney, NSW, 2036, Australia.
  • Delerue F; The University of Queensland Diamantina Institute, Translational Research Institute, The University of Queensland, Brisbane, QLD, 4102, Australia.
  • Ittner LM; Brain and Mind Research Institute, Faculty of Medicine, Sydney Medical School, The University of Sydney, Sydney, NSW, 2050, Australia.
Acta Neuropathol ; 130(5): 661-78, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26437864

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Recuperação de Função Fisiológica / Proteínas de Ligação a DNA / Degeneração Lobar Frontotemporal / Esclerose Lateral Amiotrófica / Mutação Limite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Recuperação de Função Fisiológica / Proteínas de Ligação a DNA / Degeneração Lobar Frontotemporal / Esclerose Lateral Amiotrófica / Mutação Limite: Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália