Copper-catalyzed arylation of biguanide derivatives via C-N cross-coupling reactions.
Org Biomol Chem
; 13(47): 11432-7, 2015 Dec 21.
Article
em En
| MEDLINE
| ID: mdl-26444146
ABSTRACT
An efficient copper-catalyzed cross-coupling reaction of biguanide hydrochloride derivatives with both aryl iodides and bromides under mild conditions has been developed. The reaction occurred in good yields and tolerated aryl halides containing functionalities such as nitriles, sulfonamides, ethers, and halogens. Alkyl and cyclic substituted biguanidines were also well tolerated.
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Bases de dados:
MEDLINE
Idioma:
En
Revista:
Org Biomol Chem
Assunto da revista:
BIOQUIMICA
/
QUIMICA
Ano de publicação:
2015
Tipo de documento:
Article