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Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
Losdyck, Elisabeth; Hornakova, Tekla; Springuel, Lorraine; Degryse, Sandrine; Gielen, Olga; Cools, Jan; Constantinescu, Stefan N; Flex, Elisabetta; Tartaglia, Marco; Renauld, Jean-Christophe; Knoops, Laurent.
Afiliação
  • Losdyck E; From the Ludwig Institute for Cancer Research, Brussels Branch and the de Duve Institute, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Hornakova T; From the Ludwig Institute for Cancer Research, Brussels Branch and the de Duve Institute, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Springuel L; From the Ludwig Institute for Cancer Research, Brussels Branch and the de Duve Institute, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Degryse S; the VIB Center for the Biology of Disease, K.U. Leuven, 3000 Leuven, Belgium, the K.U. Leuven Center for Human Genetics, K.U. Leuven, 3000 Leuven, Belgium.
  • Gielen O; the VIB Center for the Biology of Disease, K.U. Leuven, 3000 Leuven, Belgium, the K.U. Leuven Center for Human Genetics, K.U. Leuven, 3000 Leuven, Belgium.
  • Cools J; the VIB Center for the Biology of Disease, K.U. Leuven, 3000 Leuven, Belgium, the K.U. Leuven Center for Human Genetics, K.U. Leuven, 3000 Leuven, Belgium.
  • Constantinescu SN; From the Ludwig Institute for Cancer Research, Brussels Branch and the de Duve Institute, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Flex E; the Istituto Superiore di Sanità, 00161 Rome, Italy.
  • Tartaglia M; the Genetic Disorders and Rare Diseases Research Division, Ospedale Pediatrico Bambino Gesu' IRCCS, Viale di San Paolo 15, 00146 Rome, Italy.
  • Renauld JC; From the Ludwig Institute for Cancer Research, Brussels Branch and the de Duve Institute, Université Catholique de Louvain, 1200 Brussels, Belgium.
  • Knoops L; From the Ludwig Institute for Cancer Research, Brussels Branch and the de Duve Institute, Université Catholique de Louvain, 1200 Brussels, Belgium, the Hematology Unit, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium, and laurent.knoops@uclouvain.be.
J Biol Chem ; 290(48): 29022-34, 2015 Nov 27.
Article em En | MEDLINE | ID: mdl-26446793

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Mutação de Sentido Incorreto / Inibidores de Proteínas Quinases / Janus Quinase 3 Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Bélgica

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Mutação de Sentido Incorreto / Inibidores de Proteínas Quinases / Janus Quinase 3 Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Bélgica