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Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
Zhang, Jing; Yang, Qingyi; Cross, Jason B; Romero, Jan Antoinette C; Poutsiaka, Katherine M; Epie, Felix; Bevan, Douglas; Wang, Bin; Zhang, Yanzhi; Chavan, Ajit; Zhang, Xin; Moy, Terence; Daniel, Anu; Nguyen, Kien; Chamberlain, Brian; Carter, Nicole; Shotwell, Joseph; Silverman, Jared; Metcalf, Chester A; Ryan, Dominic; Lippa, Blaise; Dolle, Roland E.
Afiliação
  • Zhang J; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Yang Q; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Cross JB; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Romero JA; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Poutsiaka KM; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Epie F; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Bevan D; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Wang B; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Zhang Y; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Chavan A; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Zhang X; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Moy T; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Daniel A; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Nguyen K; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Chamberlain B; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Carter N; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Shotwell J; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Silverman J; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Metcalf CA; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Ryan D; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Lippa B; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
  • Dolle RE; Cubist Pharmaceuticals Inc. , Lexington, Massachusetts 02421, United States.
J Med Chem ; 58(21): 8503-12, 2015 Nov 12.
Article em En | MEDLINE | ID: mdl-26460684
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Ureia / DNA Girase / Staphylococcus aureus Resistente à Meticilina / Inibidores da Topoisomerase II / Indóis Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Ureia / DNA Girase / Staphylococcus aureus Resistente à Meticilina / Inibidores da Topoisomerase II / Indóis Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos