Predictors of Posterior Glottic Stenosis: A Multi-Institutional Case-Control Study.
Ann Otol Rhinol Laryngol
; 125(3): 257-63, 2016 Mar.
Article
em En
| MEDLINE
| ID: mdl-26466860
ABSTRACT
OBJECTIVE:
To assess intrinsic and extrinsic risk factors in the development of posterior glottic stenosis (PGS) in intubated patients.METHODS:
Patients diagnosed with PGS between September 2012 and May 2014 at 3 tertiary care university hospitals were included. Patient demographics, comorbidities, duration of intubation, endotracheal tube (ETT) size, and indication for intubation were recorded. Patients with PGS were compared to control patients represented by patients intubated in intensive care units (ICU).RESULTS:
Thirty-six PGS patients were identified. After exclusion, 28 PGS patients (14 male, 14 female) and 112 (65 male, 47 female) controls were studied. Multivariate analysis demonstrated ischemia (P < .05), diabetes (P < .01), and length of intubation (P < .01) were significant risk factors for the development of PGS. Fourteen of 14 (100%) males were intubated with a size 8 or larger ETT compared to 47 of 65 (72.3%) male controls (P < .05). Posterior glottic stenosis (P < .01), length of intubation (P < .001), and obstructive sleep apnea (P < .05) were significant risk factors for tracheostomy.CONCLUSION:
Duration of intubation, ischemia, diabetes mellitus, and large ETT size (8 or greater) in males were significant risk factors for the development of PGS. Reducing the use of size 8 ETTs and earlier planned tracheostomy in high-risk patients may reduce the incidence of PGS and improve ICU safety.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Laringoestenose
/
Intubação Intratraqueal
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ann Otol Rhinol Laryngol
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Estados Unidos