Low Quality of Life and Depressive Symptoms as an Independent Risk Factor for Erectile Dysfunction in Patients with Obstructive Sleep Apnea.
J Sex Med
; 12(11): 2168-77, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-26477542
ABSTRACT
INTRODUCTION:
Accumulating evidence indicates that obstructive sleep apnea (OSA) is associated with a high prevalence of erectile dysfunction (ED), but the factors that predict the risk of ED in OSA patients have yet to be defined clearly.AIMS:
The aims of the present study were to investigate the clinical characteristics of OSA patients with ED and to identify plausible predictors of ED.METHODS:
The present cross-sectional analysis included 713 male patients who visited Seoul National University Hospital for snoring and/or daytime sleepiness from 2006 to 2014. An in-laboratory polysomnography procedure was conducted to obtain objective recordings of OSA and other sleep parameters. MAIN OUTCOMEMEASURES:
The demographic data of all patients were obtained, and each patient completed all requirements of the following questionnaires the Calgary Sleep Apnea Quality of Life Index (SAQLI), the Korean version of the International Index of Erectile Function (KIIEF-5), the Beck Depression Inventory (BDI), and the Epworth Sleepiness Scale (ESS). ED and OSA were defined as a KIIEF-5 < 21 and a respiratory disturbance index (RDI) ≥ 5, respectively. Depressive symptoms were defined as a BDI ≥ 10.RESULTS:
The frequency of ED did not differ significantly according to OSA severity. In Spearman's correlation analysis, the BDI and the ESS were inversely correlated with the KIIEF-5, whereas the SAQLI was positively correlated with the KIIEF-5. The RDI and the lowest oxygen saturation (SaO2 ) did not exhibit significant correlations with the KIIEF-5. A multivariate logistic regression analysis adjusted for possible confounding factors showed that ED was independently associated with the SAQLI and depressive symptoms, but there was no significant association of ED with either the RDI or the lowest SaO2 .CONCLUSIONS:
The present study demonstrated that depressive symptoms and a low quality of life specific to sleep apnea are independent risk factors for ED in OSA patients.Palavras-chave
Texto completo:
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Bases de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
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Apneia Obstrutiva do Sono
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Depressão
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Disfunção Erétil
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
/
Observational_studies
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Prevalence_studies
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Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Adult
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Aged
/
Female
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Humans
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Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Sex Med
Assunto da revista:
GINECOLOGIA
/
MEDICINA REPRODUTIVA
/
UROLOGIA
Ano de publicação:
2015
Tipo de documento:
Article