Animal and cellular models of human disease.
J Pathol
; 238(2): 137-40, 2016 Jan.
Article
em En
| MEDLINE
| ID: mdl-26482929
In this eighteenth (2016) Annual Review Issue of The Journal of Pathology, we present a collection of 19 invited review articles that cover different aspects of cellular and animal models of disease. These include genetically-engineered models, chemically-induced models, naturally-occurring models, and combinations thereof, with the focus on recent methodological and conceptual developments across a wide range of human diseases.
Palavras-chave
3D xenografts; CRISPR/Cas9; HPV; MINPEPA; Wnt signalling; animal pathology reporting guidelines; atherosclerosis; behavioural testing; clear cell carcinoma; cone dystrophy; cystic fibrosis; diabetes; endometrioid carcinoma; endometriosis; epigenetic mutation; fibrosis; gasotransmitter; hydrogen sulphide; idiopathic pulmonary fibrosis; immunotherapy; incretin; inflammatory bowel disease; invasion; macular degeneration; melanoma; neurodegenerative disease; non-invasive bio-imaging; obesity; organoid culture; ovarian serous carcinoma; pancreatic ductal adenocarcinoma; patient-derived tumour xenografts; regeneration; tumour microenvironment; tumourigenesis; viral oncogenesis; xenotransplantation
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Modelos Animais de Doenças
/
Modelos Biológicos
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Pathol
Ano de publicação:
2016
Tipo de documento:
Article