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Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity 86Y- or ¹77Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates.
Cheal, Sarah M; Xu, Hong; Guo, Hong-Fen; Lee, Sang-Gyu; Punzalan, Blesida; Chalasani, Sandhya; Fung, Edward K; Jungbluth, Achim; Zanzonico, Pat B; Carrasquillo, Jorge A; O'Donoghue, Joseph; Smith-Jones, Peter M; Wittrup, K Dane; Cheung, Nai-Kong V; Larson, Steven M.
Afiliação
  • Cheal SM; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Xu H; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, 415 E. 68th Street, Z-2064, New York, NY, 10065, USA.
  • Guo HF; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lee SG; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Punzalan B; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chalasani S; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, 415 E. 68th Street, Z-2064, New York, NY, 10065, USA.
  • Fung EK; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Jungbluth A; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, 415 E. 68th Street, Z-2064, New York, NY, 10065, USA.
  • Zanzonico PB; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Carrasquillo JA; Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, 415 E. 68th Street, Z-2064, New York, NY, 10065, USA.
  • O'Donoghue J; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Smith-Jones PM; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Wittrup KD; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Cheung NV; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Larson SM; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Eur J Nucl Med Mol Imaging ; 43(5): 925-937, 2016 May.
Article em En | MEDLINE | ID: mdl-26596724
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Neoplasias Colorretais / Radioimunoterapia / Anticorpos Biespecíficos / Imunoconjugados / Compostos Radiofarmacêuticos / Afinidade de Anticorpos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Nucl Med Mol Imaging Assunto da revista: MEDICINA NUCLEAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Neoplasias Colorretais / Radioimunoterapia / Anticorpos Biespecíficos / Imunoconjugados / Compostos Radiofarmacêuticos / Afinidade de Anticorpos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Nucl Med Mol Imaging Assunto da revista: MEDICINA NUCLEAR Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos