[Clinical characteristics of patients with relapsing polychodritis].
Zhonghua Yi Xue Za Zhi
; 95(29): 2375-8, 2015 Aug 04.
Article
em Zh
| MEDLINE
| ID: mdl-26711074
ABSTRACT
OBJECTIVE:
To analyze the clinical characteristics of relapsing polychodritis (RP).METHODS:
Clinical features and laboratory data of 131 patients with RP were analyzed retrospectively.RESULTS:
The average age at onset was (44 ± 14) years (ranging from 9 to 76). Male to female ratio was 1.221. The most common onset symptom was respiratory system symptom (61.8%), followed by auricle lesions (16.0%), articular cartilage (15.3%), ocular region (7.6%), internal ear system (5.3%), nasal cartilages (4.6%), skin (2.3%) and nervous system (0.8%). During the whole course of the disease, 81.7% of the patients endured a respiratory system involvement; 77.9% and 56.5% of the patients suffered joint symptoms and nasal cartilages lesions, respectively; the involvement of auricle lesions, ocular region and internal ear system were 54.2%, 35.1% and 33.6%. Comparatively, the occurrence rates of skin lesion (10.7%), neurologic disorder (9.2%) and kidney system lesions (1.5%) were low. Analyzing of the laboratory examination data showed that 38.2% and 43.5% of the patients had an increase in white blood count (WBC) and platelet, 86.3% and 82.4% patients showed raised erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) values.CONCLUSIONS:
RP is a multi-system involvement disease, which has complicated clinical manifestations. Respiratory tract is the most common site involved, and respiratory system involvement is a prediction of unfavourable prognosis.
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Bases de dados:
MEDLINE
Assunto principal:
Doenças das Cartilagens
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Yi Xue Za Zhi
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
China