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Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.
Theodoropoulos, Panayotis C; Gonzales, Stephen S; Winterton, Sarah E; Rodriguez-Navas, Carlos; McKnight, John S; Morlock, Lorraine K; Hanson, Jordan M; Cross, Bethany; Owen, Amy E; Duan, Yingli; Moreno, Jose R; Lemoff, Andrew; Mirzaei, Hamid; Posner, Bruce A; Williams, Noelle S; Ready, Joseph M; Nijhawan, Deepak.
Afiliação
  • Theodoropoulos PC; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Gonzales SS; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Winterton SE; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Rodriguez-Navas C; Department of Molecular Genetics, UT Southwestern Medical Center, Dallas, Texas, USA.
  • McKnight JS; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Morlock LK; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Hanson JM; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Cross B; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Owen AE; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Duan Y; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Moreno JR; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Lemoff A; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Mirzaei H; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Posner BA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Williams NS; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Ready JM; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Nijhawan D; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
Nat Chem Biol ; 12(4): 218-25, 2016 Apr.
Article em En | MEDLINE | ID: mdl-26829472
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ácido Oxâmico / Estearoil-CoA Dessaturase / Benzotiazóis / Descoberta de Drogas / Neoplasias Pulmonares / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ácido Oxâmico / Estearoil-CoA Dessaturase / Benzotiazóis / Descoberta de Drogas / Neoplasias Pulmonares / Antineoplásicos Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos